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Updated: Jun 7, 2026

Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration
Published on: September 29, 2018
[Therapy-resistant, atrophic and septic femoral pseudarthrosis]
C Wedemeyer1, R Peppmüller, T Bredendiek
1Klinik für Orthopädie, Universität Duisburg-Essen, Deutschland. christian.wedemeyer@uni-duisburg-essen.de
Abstract:
Non-union is a common and serious complication in orthopaedic surgery with high socioeconomic importance. In addition to conventional methods for the treatment of non-unions bone morphogenetic protein (BMP)-7 for the induction of bone tissue is available. The case report demonstrates successful treatment of a septic and atrophic femoral non-union by combination therapy with BMP-7 and autologous spongiosa graft after multiple revision surgeries.