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Updated: Jun 7, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
[Unilateral blurred vision associated with combined macular and papillary edema: a 34-year-old male patient]
T U Krohne1, A C Bird, M Friedlander
1Division of Ophthalmology, Scripps Clinic Torrey Pines, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. krohne@scripps.edu
Abstract:
We present clinical images of a case of Leber's idiopathic stellate neuroretinitis (LISN). A 34-year-old male presented with acute-onset unilateral blurred vision for 5 days. Clinical examination revealed sectorial papillary edema and extensive macular edema in the affected eye. Using optical coherence tomography we detected intraretinal fluid in the outer retinal layers and subretinal fluid under the fovea. Seven days later, the macular edema was completely resolved, and disseminated retinal exudates had appeared, resembling a macular star figure. No underlying systemic disease was identified. Follow-up examination after 3 months demonstrated almost complete spontaneous resolution of fundus changes and near-normalization of visual acuity.
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