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Updated: Jun 7, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Is colonization with GBS in a previous pregnancy associated with adverse perinatal outcomes?
Adi Y Weintraub1, Roy Kessous, Ruslan Sergienko
1Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Objective:
To investigate whether colonization with GBS in a previous pregnancy is associated subsequently with adverse obstetric and perinatal outcomes.
Methods:
A retrospective study was undertaken comparing pregnancy complications of patients with and without colonization with GBS in a previous pregnancy from 1988 to 2006. Women with a positive GBS culture in the current pregnancy, women lacking prenatal care and multiple gestations were excluded from the analysis.
Main Outcome Measures:
Adverse obstetric and perinatal outcomes including premature rupture of membranes, intrapartum fever, chorioamnionitis and perinatal mortality.
Results:
Out of 184,266 singleton deliveries, 230 (0.12%) were of patients with a positive GBS culture in their previous pregnancy. Previous GBS colonization was not found to be associated with adverse pregnancy outcomes such as PROM (9.1 vs. 6.8%; P = 0.16), intrapartum fever (1.3 vs. 2.2%; P = 0.72) and chorioamnionitis (1.3 vs. 0.8%; P = 0.29).
Conclusions:
GBS colonization in a previous pregnancy is not associated with adverse pregnancy outcomes in the current pregnancy.
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