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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
Diagnosis of allergy and asthma in childhood
Carlos E Baena-Cagnani1, Héctor A Badellino
1CIMER (Centro de Investigación en Medicina Respiratoria), Catholic University of Córdoba, Santa Rosa 381, X 5000 ESG, Córdoba, Argentina. cebaenac@fundacionlibra.org
Insights
Diagnosing asthma in young children is challenging due to developmental factors. Early and accurate diagnosis is crucial for effective treatment and managing childhood asthma symptoms.
Area of Science:
- Pediatric Pulmonology
- Allergy and Immunology
- Respiratory Medicine
Background:
- Childhood asthma affects over 300 million globally, with many cases originating in early life.
- Diagnosing asthma in preschool children presents unique challenges compared to older children and adults.
- Factors like lung development, environmental influences, and immune maturation complicate early asthma detection.
Purpose of the Study:
- To review current knowledge on early and accurate asthma diagnosis in preschool children.
- To guide appropriate treatment decisions for improved asthma symptom control.
- To minimize long-term health risks associated with undiagnosed or misdiagnosed childhood asthma.
Main Methods:
- Literature review of cross-sectional and cohort studies.
- Analysis of diagnostic challenges specific to the preschool age group.
- Synthesis of current understanding of asthma in early childhood.
Main Results:
- Asthma diagnosis is more complex in preschool children than in older age groups.
- Specific developmental and environmental factors impede straightforward diagnosis.
- Accurate diagnosis is essential for timely intervention.
Conclusions:
- Early and precise diagnosis is key to effective management of childhood asthma.
- Addressing diagnostic challenges in preschoolers is vital for optimal health outcomes.
- This review provides insights for pediatricians and specialists managing early-life asthma.
Abstract:
Childhood asthma is a widespread health problem because of its epidemic prevalence, as asthma affects more than 300 million people worldwide. Results from cross-sectional and cohort studies show that asthma starts in childhood in a large proportion of cases. A proper diagnosis is easier to make in adults and school-age children, as permanent changes in lung development, the strong impact of environmental factors on the airways, the immunologic maturity process, and the use of some diagnostic tools make asthma more difficult to diagnose in preschool children. This period of a child's life is an interesting challenge for pediatricians and specialists. The aim of the present review is to analyze the current knowledge regarding making an early and accurate asthma diagnosis and therefore deciding on the correct treatment to gain control over asthma symptoms and minimize health risks.
Related Concept Videos
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma I: Introduction
Asthma-I: Introduction
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma III: Clinical Manifestations

