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Updated: Jun 7, 2026
Quantitation of Intra-peritoneal Ovarian Cancer Metastasis
Published on: July 18, 2016
Extraovarian peritoneal serous papillary carcinoma: a case report
Sophia Veroni1, Kalliopi Terzopoulou, Irene Anagnostopoulou
1Department of Cytopathology, "Tzanio" General Hospital of Pireas, Afentouli and Zanni, 18536 Pireas, Greece. eirinidoct@yahoo.gr
Background:
Extraovarian peritoneal serous papillary carcinoma (EPSPC) is a rare cancer closely related to ovarian carcinoma and characterized by abdominal carcinomatosis without an identifiable abdominal primary tumor.
Case:
A woman presented with ascites. She had an elevated serum CA-125. Peritoneal carcinomatosis without involvement of the ovaries was found. Paracentesis of the ascitic fluid resulted in a positive cytologic report not further suggestive of the malignancy origin, balancing between a mesothelioma and an adenocarcinoma. The histologic and immunohistochemical study of peritoneal biopsy specimens resulted in the diagnosis of EPSPC.
Conclusion:
The combination of cytology, histology, immunohistochemistry and clinical data is a reliable method for the preoperative diagnosis of EPSPC, allowing prompt chemotherapy as surgery may not be indicated in most cases.
