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Updated: Jun 7, 2026
09:31
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Clinical predictors of renal mass pathological features
Matvey Tsivian1, Vladimir Mouraviev1, David M Albala1
1Division of Urology, Department of SurgeryDepartment of Pathology, Duke University Medical Center, Durham, NC, USA.
BJU International
|November 9, 2010
Summary
Preoperative factors like age, male gender, and tumor size predict aggressive kidney cancer. These indicators help in managing solitary enhancing renal masses and choosing appropriate treatment options.
Area of Science:
- Urology
- Oncology
- Radiology
Background:
- Renal masses require accurate preoperative risk stratification to guide management.
- Identifying predictors of aggressive pathology is crucial for clinical decision-making.
Purpose of the Study:
- To determine how radiographic tumor size and other preoperative variables influence pathological characteristics of renal lesions.
- To assess preoperative risk factors for aggressive versus indolent renal masses.
Main Methods:
- Retrospective review of 768 patients with single, sporadic renal masses (2000-2008).
- Analysis of demographic, radiographic, and pathological variables using regression analyses.
- Identification of risk factors for malignant pathology, high Fuhrman grade, and local invasion.
Main Results:
- Malignancy confirmed in 81.8% of specimens.
- Radiographic size significantly correlated with malignancy, high Fuhrman grade, vascular invasion, and extracapsular extension.
- Age, symptomatic presentation, solid appearance, and radiographic size independently predicted aggressive disease.
Conclusions:
- Age, male gender, radiographic size and appearance, and symptomatic presentation are associated with increased risk of aggressive renal malignancy.
- These factors are important considerations for managing solitary enhancing renal masses.
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