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Related Experiment Video

Updated: Jun 6, 2026

Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder

Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder

Published on: July 7, 2023

Stigma and functioning in patients with bipolar disorder.

G H Vázquez¹, F Kapczinski, P V Magalhaes

¹Department of Neuroscience, University of Palermo, Buenos Aires, Argentina. gvazquez@palermo.edu

Journal of Affective Disorders

|November 9, 2010

Summary

Self-perceived stigma significantly impacts functioning in individuals with bipolar disorder in Latin America. This study highlights the crucial link between stigma experiences and daily life challenges for patients.

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Last Updated: Jun 6, 2026

Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder

Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder

Published on: July 7, 2023

Area of Science:

Psychiatry
Mental Health Research
Clinical Psychology

Background:

Bipolar disorder is a chronic mental illness affecting millions globally.
Stigma remains a significant barrier to treatment and recovery for individuals with bipolar disorder.
Understanding the relationship between stigma and functioning is crucial for developing effective interventions.

Purpose of the Study:

To investigate the impact of self-rated stigma on functioning in bipolar disorder patients across Latin America.
To identify factors associated with self-perceived stigma in this population.

Main Methods:

Recruited 241 participants with bipolar disorder from Argentina, Brazil, and Colombia.
Assessed functional impairment using the Functioning Assessment Short Test (FAST).
Evaluated perceived stigma using the Inventory of Stigmatizing Experiences (ISE).

Main Results:

A significant negative correlation was found between self-perceived stigma and functioning.
Multiple regression analysis indicated that disability benefit status, current mood symptoms, and functioning were associated with self-perceived stigma.

Conclusions:

This study provides the first evidence of an association between stigma and poor functioning in bipolar disorder.
Findings suggest that addressing stigma is essential for improving functional outcomes in bipolar disorder patients.
Implications for clinical practice and future research are discussed.