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Updated: Jun 6, 2026

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats
Published on: March 8, 2019
A case of primary pulmonary hypertension with pulmonary tumor
Masaomi Ichinokawa1, Yasuhiro Hida, Kichizo Kaga
1Department of Surgical Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
Abstract:
A 64-year-old female with a 9-year history of primary pulmonary hypertension developed a solid pulmonary tumor. Partial lung resection was planned for diagnosis. Although prostacyclin was increased to 8 ng/kg/min, she did not tolerate the decubitus position and one-lung ventilation, and her pulmonary arterial pressure rose to 110/45 mmHg. While she underwent partial resection under two-lung ventilation in the decubitus position, bleeding occurred from the suture line closed by a linear stapler and was controlled by additional sutures. She was discharged home without postoperative complications on postoperative day 15. The pathological examination revealed a bronchioloalveolar carcinoma. If pulmonary resection becomes necessary in a similar patient, we will plan a partial resection with the patient in a supine position to prevent elevation of pulmonary arterial pressure.
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