Related Experiment Video
Updated: Jun 6, 2026
10:26
A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
[Individualized "minimal invasive" anticoagulation controlled with D-dimer-antigen testing - a concept]
W Müller-Beissenhirtz1, H Boschert, H Müller-Beissenhirtz
1Medizinisches Versorgungszentrum, Labor Ludwigsburg.
Hamostaseologie
|November 9, 2010
Summary
This study proposes individualized anticoagulant therapy to minimize coagulation activation, reducing bleeding risks. Monitoring D-dimer levels ensures tailored treatment for preventing thromboembolic events.
Area of Science:
- Hematology
- Pharmacology
- Clinical Medicine
Context:
- Thromboembolic events pose significant health risks.
- Current anticoagulant therapies carry bleeding risks, limiting their use.
- Newer oral anticoagulants offer potential for safer treatment.
Purpose:
- To introduce a concept for individualized anticoagulant therapy.
- To tailor anticoagulation to a patient's specific coagulation activation.
- To minimize bleeding risk while effectively preventing thromboembolic events.
Summary:
- The proposed concept involves using anticoagulant therapy only to the point where coagulation activation is undetectable.
- This individualized "minimal invasive" anticoagulation is monitored by measuring in vivo coagulation activation, such as D-dimer-antigen levels.
- This approach aims to reduce bleeding complications and potentially expand indications for anticoagulant use.
Impact:
- Could enable safer anticoagulant therapy, reducing bleeding risks.
- May open new therapeutic indications currently limited by safety concerns.
- Potentially prevents more patients at risk from experiencing thromboembolic events.
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