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Published on: July 28, 2010
Richter's syndrome in colon: case report.
Alfonso Chacaltana Mendoza1, Julio Espinoza García
1Division of Gastroenterology, Peruvian Japanese Centenary Clinic, Av. Paso de los Andes 675, Pueblo Libre, Lima 21, Peru. dralfonso_al@yahoo.com
Journal of Gastrointestinal Cancer
|November 9, 2010
Summary
Richter's syndrome, a serious complication of chronic lymphocytic leukemia, rarely involves the gastrointestinal tract. This case highlights lower gastrointestinal bleeding due to colonic involvement of Richter's syndrome.
Area of Science:
- Hematology
- Oncology
- Gastroenterology
Background:
- Richter's syndrome is the development of diffuse large B cell lymphoma in patients with chronic lymphocytic leukemia.
- It is a rare but serious complication, typically affecting lymphoid tissues.
- Extranodal involvement, particularly in the gastrointestinal tract, is uncommon.
Observation:
- A 61-year-old patient presented with lower gastrointestinal bleeding.
- The bleeding was attributed to colonic involvement of Richter's syndrome.
Findings:
- This case demonstrates an unusual presentation of Richter's syndrome with significant colonic manifestation.
- The patient experienced lower gastrointestinal bleeding as the primary symptom.
Implications:
- Highlights the importance of considering extranodal Richter's syndrome in patients with chronic lymphocytic leukemia presenting with gastrointestinal symptoms.
- Underscores the need for thorough investigation of gastrointestinal bleeding in this patient population.
- Contributes to understanding the diverse clinical manifestations of Richter's syndrome.
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