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Behavioural treatment programme contributes to normalization of contingent negative variation in children with

Michael Siniatchkin1, Gabriele Gerber-von Müller, Stephani Darabaneanu

  • 1Neuropaediatric Department, Paediatric Hospital, Christian-Albrechts-University, Schwanenweg 20, Kiel, Germany. m.siniatchkin@pedneuro.uni-kiel.de

Cephalalgia : an International Journal of Headache
|November 10, 2010
PubMed

Insights

Migraine patients showed improved habituation with special behavioral training (MIPAS-Family). This migraine treatment enhanced central information processing and reduced headache frequency, unlike biofeedback.

Area of Science:

  • Neuroscience
  • Pediatric Neurology
  • Behavioral Medicine

Background:

  • Migraine is linked to central information processing abnormalities, including altered evoked potentials.
  • Habituation deficits in event-related potentials are observed in migraine patients.
  • A novel behavioral training program, MIPAS-Family (Migraine Patient Seminar for Families), was developed for children with migraine without aura.

Purpose of the Study:

  • To evaluate the effectiveness of MIPAS-Family training on central information processing in pediatric migraine.
  • To compare the effects of MIPAS-Family training with biofeedback on migraine characteristics and cortical processing.

Main Methods:

  • A pilot study involving 13 children with migraine undergoing MIPAS-Family training.
  • A comparison group of 13 children with migraine received biofeedback treatment.
  • Cortical information processing was assessed using contingent negative variation (CNV) recordings.

Main Results:

  • Both MIPAS-Family and biofeedback reduced migraine frequency and severity equally.
  • MIPAS-Family treatment significantly increased CNV habituation, unlike biofeedback.
  • Improved habituation correlated positively with reduced headache frequency in the MIPAS-Family group.

Conclusions:

  • MIPAS-Family training, derived from migraine's pathogenetic mechanisms, positively influences central information processing.
  • This behavioral intervention leads to significant clinical improvements in pediatric migraine patients.
  • Specific training targeting habituation deficits offers a promising therapeutic approach for migraine.
Abstract

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