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Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
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Cycloaddition chemistry of allenamides

Patricia E Standen1, Marc C Kimber

  • 1Loughborough University, Department of Chemistry, Leicestershire, LE11 3TU, UK.

Current Opinion in Drug Discovery & Development
|November 10, 2010
PubMed
Summary

Allenamides, electron-deficient synthons, are versatile in cycloaddition reactions for creating novel heterocycles. This review highlights their applications and stereochemical prediction in synthesizing complex molecular architectures.

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