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Catalytic Reactions at Amine-Stabilized and Ligand-Free Platinum Nanoparticles Supported on Titania During Hydrogenation of Alkenes and Aldehydes
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Homogenous asymmetric hydrogenation: Recent trends and industrial applications

Andreas M Palmer1, Antonio Zanotti-Gerosa

  • 1Nycomed GmbH, Department of Medicinal Chemistry, Byk-Gulden-Strasse 2, D-78467 Konstanz, Germany. andreas.palmer@nycomed.com

Current Opinion in Drug Discovery & Development
|November 10, 2010
PubMed

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The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
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