Related Experiment Video
Updated: Jun 6, 2026

Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance
Published on: March 7, 2025
[Epidemiology of peptic ulcer in the elderly]
Yuji Mizokami1, Junichi Iwamoto
1Department of Gastroenterology and Endoscopy, University of Tsukuba.
Abstract:
The frequency of severe complications is higher in elderly patients than in young patients. NSAIDs and low-dose aspirin are often prescribed for elderly patients. Physiological functions of the stomach such as acid secretion in elderly patients are also different from those in young patients. Hemorrhage and perforation can suddenly occur in elderly patients even though abdominal symptoms are mild. There is a tendency for the condition of such patients to deteriorate and long-term hospitalization is often required. Effective prevention measures are necessary since it is expected that cases of gastrointestinal injury caused by NSAIDs will continue to increase.
Related Concept Videos
Peptic Ulcer Disease III: Clinical Manifestations and Complications
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Peptic Ulcer Disease I: Introduction
Peptic Ulcer Disease II: Pathophysiology
Peptic Ulcer Disease II: Pathophysiology
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
Peptic Ulcer