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Quantitation of Intra-peritoneal Ovarian Cancer Metastasis
Published on: July 18, 2016
Normal-sized ovarian papillary serous carcinoma: a case report
1Department of Obstetrics and Gynecology, China Medical University Hospital, Taichung, Taiwan.
European Journal of Gynaecological Oncology
|November 11, 2010
Summary
Normal-sized ovarian papillary serous carcinoma, though rare, can cause abdominal carcinomatosis. Early diagnosis is crucial for effective treatment of this ovarian cancer subtype.
Area of Science:
- Gynecology
- Oncology
- Pathology
Background:
- Ovarian papillary serous carcinoma typically presents with enlarged ovaries.
- Normal-sized ovarian tumors are infrequently associated with advanced peritoneal carcinomatosis.
Observation:
- A 46-year-old woman presented with abdominal fullness and carcinomatosis despite normal-sized ovaries.
- Serum cancer antigen 125 (CA-125) levels were significantly elevated at 147,365.8 U/ml.
Findings:
- Histologic examination confirmed ovarian serous papillary carcinoma.
- Cytoreductive surgery followed by adjuvant chemotherapy led to a decrease in serum CA-125 levels.
Implications:
- Normal-sized ovarian papillary serous carcinoma should be considered in cases of unexplained peritoneal carcinomatosis.
- This emphasizes the need for vigilant diagnosis of subtle ovarian cancer presentations.
- Accurate and timely diagnosis is vital for managing this rare condition.
