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Genital Herpes01:23

Genital Herpes

Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...
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External Female Genitals

The vulva encompasses the external structures of the female reproductive system. At the forefront is the monpubis, a cushion of fatty tissue atop the pubic bone. Once puberty sets in, this area typically grows hair. Extending from just behind the mons pubis are the labia majora (labia = 'lips'; majora = 'larger'), which are larger skin fs olds coated with hair. Nestled within are the labia minora (labia = 'lips'; minora = 'smaller'), which are thinner, more pigmented, and hairless. While the...
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Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
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Chickenpox is an acute, highly contagious disease caused by the varicella-zoster virus (VZV), a double-stranded DNA virus belonging to the Herpesviridae family. Its transmission occurs primarily through the inhalation of respiratory droplets or direct contact with vesicular fluid from skin lesions. The incubation period typically ranges from 10 to 21 days, during which the virus replicates and disseminates through sequential phases within the host. Although generally self-limiting in children,...
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Vulvar puritus for one year.

Nina A Madnani1, Ashwini Bhalerao-Gandhi, Kaleem J Khan

  • 1P D Hinduja National Hospital, Mumbai, Maharashtra, India.

Dermatology Online Journal
|November 11, 2010
PubMed
Summary

A persistent vulvar lesion in a menopausal woman, initially treated for infection, was diagnosed via biopsy. Histopathology revealed findings consistent with a specific dermatological condition, necessitating further investigation.

Area of Science:

  • Dermatology
  • Gynecology
  • Pathology

Background:

  • Persistent vulvar itching and a slowly growing whitish lesion are concerning symptoms in postmenopausal women.
  • Previous treatments with antifungal and combination topical steroids were ineffective.

Observation:

  • A 60-year-old menopausal female presented with a year-long history of vulvar itching and a whitish plaque.
  • The lesion involved the labia minora, clitoris, and peri-urethral area.
  • Standard microbiological and serological tests were negative.

Findings:

  • Histopathological examination of a punch biopsy was performed.
  • Microscopic findings from the biopsy are presented in Figures 2 and 3.

Implications:

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  • Accurate diagnosis through biopsy is crucial for appropriate management of persistent vulvar lesions.
  • The histopathological findings will guide further treatment strategies.