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Eryngium foetidum L.: a review
J H A Paul1, C E Seaforth, T Tikasingh
1Caribbean Herbal Medicine Research Institute, The University of Trinidad and Tobago, Waterloo Research Centre, WI Central Trinidad, Trinidad and Tobago. jennifer.paul@utt.edu.tt
Fitoterapia
|November 11, 2010
Summary
Eryngium foetidum L., a medicinal herb, shows significant anthelmintic, anti-inflammatory, and antibacterial properties. Its key compound, eryngial, is being explored for various therapeutic applications in humans and mammals.
Area of Science:
- Ethnobotany
- Phytochemistry
- Pharmacology
Background:
- Eryngium foetidum L. is a biennial herb widely used in tropical regions for medicinal purposes and as a spice.
- It has diverse ethnomedicinal applications, including treatments for infections, inflammatory conditions, and gastrointestinal issues.
- Chemical analysis reveals flavonoids, tannins, saponins, and triterpenoids, with E-2-dodecenal (eryngial) as a major essential oil component.
Purpose of the Study:
- To investigate the phytochemical composition and pharmacological activities of Eryngium foetidum L.
- To explore the potential therapeutic applications of its active compounds, particularly eryngial.
- To highlight the variability in essential oil composition based on geographic origin.
Main Methods:
- Chemical evaluation of leaf constituents.
- Analysis of essential oil composition.
- Pharmacological screening of aerial plant parts and essential oil fractions.
Main Results:
- The essential oil contains significant amounts of E-2-dodecenal (eryngial) and lesser amounts of trimethylbenzaldehyde isomers.
- Pharmacological studies demonstrated anthelmintic activity (eryngial), anti-inflammatory effects (phytosterols), anticonvulsant properties, and selective antibacterial activity against Salmonella and Erwinia.
- A fraction rich in eryngial is patented for its efficacy against trypanosomes, nematodes, fungi, and bacteria.
Conclusions:
- Eryngium foetidum L. possesses a range of valuable pharmacological activities, including anthelmintic, anti-inflammatory, and antimicrobial properties.
- Eryngial is a key bioactive compound with potential applications in treating parasitic, fungal, and bacterial infections.
- Further research into Eryngium foetidum L. and its derivatives is warranted for developing new therapeutic agents.
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