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Tissue-type plasminogen activator: intracoronary applications.
1Cardiovascular Division, Washington University School of Medicine, St. Louis, MO 63110.
Catheterization and Cardiovascular Diagnosis
|February 1, 1990
Summary
Intracoronary tissue-type plasminogen activator (t-PA) effectively treated evolving myocardial infarction in four patients, either before, after, or instead of angioplasty. This study explores intracoronary thrombolysis roles and safety for heart attack patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Thrombolytic Therapy
Background:
- Myocardial infarction (MI) remains a leading cause of mortality.
- Timely reperfusion is critical for preserving myocardial function.
- Coronary artery angioplasty is a primary reperfusion strategy, but alternatives are needed.