Related Experiment Video
Updated: Jun 6, 2026

Evaluating the Effect of Environmental Chemicals on Honey Bee Development from the Individual to Colony Level
Published on: April 1, 2017
Abnormal glucose regulation in pyrethroid pesticide factory workers
Jinsong Wang1, Yueqian Zhu, Xiang Cai
1Department of Preventive Medicine, Medical College, Yangzhou University, China. yzdewjs@163.com
Abstract:
The purpose of this study was to investigate associations between pyrethroids occupational exposures, and risk of abnormal glucose regulation. Data from total of 3080 subjects in two pesticide factories were used. This was a population-based case-controlled study in China. In total, 18.3% of subjects with impaired glucose regulation (IGR) and 6.5% of subjects with diabetes, and the prevalence of abnormal glucose regulation was 24.8%, 86 subjects had known type 2 diabetes and 114 had newly diagnosed diabetes. The prevalence of subjects with abnormal glucose regulation increased from 21.3% in the controls to 29.3% in the exposures (χ² = 33.182, P < 0.001). Multivariate logistic regression was used to control potential confounders and calculate odd ratios as the estimate of effect. An indication of increased risk for abnormal glucose regulation was noted for exposure to pyrethroids (OR = 1.482, 95%CI = 1.238-1.774). Abnormal glucose regulation is common in subjects exposed to pyrethroids. The present investigation indicates the adverse health effects of pyrethroids are underestimated.
Related Concept Videos
Hyperglycemia
Hypoglycemia and Glucagon
Type I Diabetes III: Clinical Manifestations
Hypoglycemia
Glucose Transporters
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
Inborn Errors of Metabolism

