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Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Contrast-enhanced computed tomographic and echocardiographic detection of intra-aortic floating thrombus causing
Tsunenari Soeda1, Satoshi Okayama, Ayako Seno
1First Department of Internal Medicine, Nara Medical University, Kashihara, Nara, Japan.
Insights
A rare case of acute myocardial infarction (AMI) caused by left main coronary artery (LMCA) occlusion from an intra-aortic thrombus is presented. This unusual thrombus formation led to a fatal outcome despite intervention.
Area of Science:
- Cardiology
- Vascular Medicine
- Diagnostic Imaging
Background:
- Acute myocardial infarction (AMI) typically results from coronary artery atherosclerosis.
- Left main coronary artery (LMCA) occlusion is a rare but catastrophic cause of AMI.
Observation:
- A 51-year-old man presented with symptoms suggestive of AMI.
- Coronary angiography showed no native coronary lesions.
- Computed tomography (CT) and echocardiography identified an intra-aortic thrombus near the LMCA ostium.
Findings:
- The intra-aortic thrombus was determined to be the cause of LMCA occlusion and subsequent AMI.
- Despite stent implantation to maintain LMCA patency, the patient succumbed to sepsis.
- Post-mortem examination confirmed the thrombus was attached to an atherosclerotic aortic wall.
Implications:
- This case highlights an unusual etiology for LMCA occlusion and AMI.
- Intra-aortic thrombus formation requires consideration in the differential diagnosis of acute coronary syndromes.
- Atherosclerotic aortic disease can be a substrate for thrombus formation causing coronary occlusion.
Abstract:
We present the rare case of a 51-year-old man with acute myocardial infarction (AMI) caused by left main coronary artery (LMCA) occlusion due to intra-aortic thrombus. He arrived at our hospital with sudden left precordial oppression. Transcatheter coronary angiography for suspected AMI detected no coronary lesions. After 10 minutes, noncontrast computed tomography (CT) confirmed significantly high transmural attenuation areas suggesting myocardial infarction in the septal, anterior and lateral wall. Contrast-enhanced CT and transesophageal echocardiography detected a small mass near the ostium of the LMCA in the coronary sinus of Valsalva. We thus considered that the mass occluded the LMCA, which led to AMI. A stent was implanted to prevent the mass from sealing the LMCA ostium, but the patient died of sepsis. A post-mortem examination clarified that the mass was a red thrombus attached to an erosive and atherosclerotic aortic wall.
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