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Published on: June 2, 2014
The use of ID migraine™ questionnaire in patients with multiple sclerosis
Veronica Villani1, Luca Prosperini, Carlo Pozzilli
1Neurological Headache Centre, S. Andrea Hospital, La Sapienza University, Rome, Italy. veronicavillani@hotmail.it
Abstract:
Primary headaches are underdiagnosed and undertreated in patients with multiple sclerosis (MS). The aim of our study was to investigate the possibility of using the ID migraine™ (ID-M) questionnaire to make a first-line diagnosis of migraine in subjects affected by MS. We consecutively recruited 144 patients regularly attending the MS Centre of S. Andrea Hospital in Rome. Results from ID-M were matched with diagnoses of a blind neurologist. According to the ICHD-II criteria, 77 (53.5%) patients were diagnosed as suffering from migraine. ID-M showed high sensitivity (91%) and specificity (94%) in identifying patients with migraine. ID-M was also able to discriminate patients affected by headache following interferon beta therapy, having only the 10% out of these patients a positive ID-M. The use of the ID-M as a screening test is warranted not only in the epidemiological research, but also to ensure a better clinical management of patients with MS.
Insights
The ID migraine™ (ID-M) questionnaire effectively screens for migraine in multiple sclerosis (MS) patients, aiding diagnosis and improving clinical management. This tool demonstrates high accuracy in identifying migraine headaches in individuals with MS.
Area of Science:
- Neurology
- Clinical Diagnostics
Background:
- Primary headaches, particularly migraine, are frequently underdiagnosed and undertreated in patients with multiple sclerosis (MS).
- Accurate and efficient diagnostic tools are crucial for improving patient care in this population.
Purpose of the Study:
- To evaluate the utility of the ID migraine™ (ID-M) questionnaire for the first-line diagnosis of migraine in patients with MS.
- To assess the sensitivity and specificity of the ID-M questionnaire in this specific patient group.
Main Methods:
- A consecutive cohort of 144 patients attending an MS Centre were recruited.
- ID-M questionnaire results were compared against diagnoses made by a neurologist blinded to the questionnaire results, using ICHD-II criteria.
Main Results:
- Migraine was diagnosed in 77 (53.5%) of the MS patients according to ICHD-II criteria.
- The ID-M questionnaire exhibited high sensitivity (91%) and specificity (94%) for migraine detection in MS patients.
- The ID-M questionnaire effectively differentiated migraine from headaches associated with interferon beta therapy, with only 10% of such patients testing positive.
Conclusions:
- The ID migraine™ questionnaire is a valuable screening tool for diagnosing migraine in patients with multiple sclerosis.
- Implementing the ID-M questionnaire can enhance both epidemiological research and clinical management strategies for MS patients experiencing headaches.
