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Related Concept Videos

Factors Influencing the Rate of Chemical Reactions01:22

Factors Influencing the Rate of Chemical Reactions

A variety of factors influence the rate of chemical reactions. For a chemical reaction to happen, atoms must collide with enough energy to overcome the repulsion between their electrons. This energy is called activation energy. Factors influencing the rate of reaction either lower the activation energy or increase the likelihood of a successful collision.
Concentration and Pressure:
The more particles present within a given space, the more likely those particles are to bump into one another.
Introduction to Mechanisms of Enzyme Catalysis01:13

Introduction to Mechanisms of Enzyme Catalysis

For many years, scientists thought that enzyme-substrate binding took place in a simple "lock-and-key" fashion. This model stated that the enzyme and substrate fit together perfectly in one instantaneous step. However, current research supports a more refined view scientists call induced fit. The induced-fit model expands upon the lock-and-key model by describing a more dynamic interaction between enzyme and substrate. As the enzyme and substrate come together, their interaction causes a mild...
Introduction to Mechanisms of Enzyme Catalysis01:13

Introduction to Mechanisms of Enzyme Catalysis

For many years, scientists thought that enzyme-substrate binding took place in a simple "lock-and-key" fashion. This model stated that the enzyme and substrate fit together perfectly in one instantaneous step. However, current research supports a more refined view scientists call induced fit. The induced-fit model expands upon the lock-and-key model by describing a more dynamic interaction between enzyme and substrate. As the enzyme and substrate come together, their interaction causes a mild...
Catalysis01:27

Catalysis

Catalysis influences the rate of chemical reactions by providing an alternative reaction pathway with lower activation energy. A catalyst speeds up a reaction, but it is not consumed during the process. The fundamental principle of catalysis is the ability of a catalyst to alter the reaction mechanism, often introducing a more efficient pathway than the uncatalyzed process.In a catalyzed reaction, the catalyst participates directly in the reaction mechanism. It interacts with reactants to form...
Catalysis02:50

Catalysis

The presence of a catalyst affects the rate of a chemical reaction. A catalyst is a substance that can increase the reaction rate without being consumed during the process. A basic comprehension of a catalysts’ role during chemical reactions can be understood from the concept of reaction mechanisms and energy diagrams.
Cofactors and Coenzymes01:27

Cofactors and Coenzymes

Enzymes require additional components for proper function. There are two such classes of molecules: cofactors and coenzymes. Cofactors are metallic ions and coenzymes are non-protein organic molecules. Both of these types of helper molecule can be tightly bound to the enzyme or bound only when the substrate binds.

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Related Experiment Video

Updated: Jun 6, 2026

Functional Complementation Analysis (FCA): A Laboratory Exercise Designed and Implemented to Supplement the Teaching of Biochemical Pathways
09:27

Functional Complementation Analysis (FCA): A Laboratory Exercise Designed and Implemented to Supplement the Teaching of Biochemical Pathways

Published on: June 24, 2016

Accessory food factors: understanding the catalytic function.

Robyn Braun1

  • 1Department of Sociology and Science, University of Alberta, Edmonton, Canada. robyn.braun@ualberta.ca

Journal of the History of Biology
|November 12, 2010
PubMed
Summary
This summary is machine-generated.

The discovery of vitamins was delayed because researchers focused on germ theory, overlooking their catalytic role. Understanding vitamins as catalysts unlocked new physiological insights previously inaccessible.

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Last Updated: Jun 6, 2026

Functional Complementation Analysis (FCA): A Laboratory Exercise Designed and Implemented to Supplement the Teaching of Biochemical Pathways
09:27

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Published on: June 24, 2016

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The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis

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Expression, Purification, Crystallization, and Enzyme Assays of Fumarylacetoacetate Hydrolase Domain-Containing Proteins

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Area of Science:

  • Biochemistry
  • Nutritional Science
  • History of Science

Background:

  • Practical knowledge of dietary cures for scurvy, rickets, and beriberi existed in the 19th century.
  • The concept of 'accessory food factors' emerged in 1901, but vitamin discovery was delayed.
  • The prevailing germ theory and auto-intoxication theories hindered the recognition of vitamins.

Discussion:

  • This paper argues that the delay in vitamin discovery was not solely due to the germ theory.
  • It highlights the crucial role of understanding vitamins' catalytic function in advancing physiology.
  • The catalytic nature of vitamins made them conceptually inaccessible within Bernardian physiology frameworks.

Key Insights:

  • Vitamins were discovered late due to a conceptual barrier, not just scientific dogma.
  • Recognizing the catalytic role of vitamins revolutionized physiological understanding.
  • The concept of vitamins was systematically inaccessible before their catalytic function was appreciated.

Outlook:

  • Further research can explore how other fundamental biological concepts were similarly hindered by prevailing scientific paradigms.
  • Understanding historical conceptual barriers can inform future scientific discovery.
  • This perspective offers a new lens for examining the history of nutritional science and biochemistry.