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Microsporidial keratitis: need for increased awareness

Savitri Sharma1, Sujata Das, Joveeta Joseph

  • 1L.V. Prasad Eye Institute, Bhubaneswar, Orissa, India. savitri@lvpei.org

Survey of Ophthalmology
|November 13, 2010
PubMed

Insights

Microsporidia cause serious eye infections, particularly in the cornea, affecting both healthy and immunocompromised individuals. These infections are common in rainy seasons, especially in tropical climates.

Area of Science:

  • Microbiology
  • Ophthalmology
  • Infectious Diseases

Background:

  • Microsporidia are significant pathogens, historically impacting the European silkworm industry.
  • Recent decades show increased attention to ocular microsporidiosis, especially corneal infections.
  • Ocular microsporidial infections affect both immunocompetent and immunocompromised patients.

Purpose of the Study:

  • To review and synthesize current knowledge on ocular microsporidiosis.
  • To highlight the increasing incidence and clinical significance of microsporidial eye infections.
  • To consolidate information on diagnosis, treatment, and risk factors for ocular microsporidiosis.

Main Methods:

  • Literature review of publications on ocular microsporidiosis.
  • Analysis of clinical presentations, from mild keratoconjunctivitis to severe keratitis.
  • Examination of epidemiological data and risk factors, including environmental exposures.

Main Results:

  • Ocular microsporidiosis can manifest as mild to severe corneal disease.
  • Risk factors include exposure to soil, water, and minor eye trauma.
  • High prevalence observed during rainy seasons, particularly in India and Singapore.

Conclusions:

  • Ocular microsporidiosis is an emerging concern in ophthalmology.
  • Prompt diagnosis and treatment are crucial for managing these infections.
  • Further research is needed to establish accurate prevalence data and refine treatment strategies.

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