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Updated: Jun 6, 2026

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Published on: November 30, 2022

GenBank.

Dennis A Benson¹, Ilene Karsch-Mizrachi, David J Lipman

¹National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.

Nucleic Acids Research

|November 13, 2010

Summary

This summary is machine-generated.

GenBank is a vital nucleotide sequence database covering over 380,000 organisms. It facilitates global research through daily data exchange and integrated analysis tools.

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Area of Science:

Bioinformatics
Genomics
Molecular Biology

Background:

GenBank is a comprehensive public repository for nucleotide sequences.
It archives data from diverse sources, including individual labs and large-scale sequencing projects.
The database supports over 380,000 unique organisms.

Purpose of the Study:

To describe the scope and accessibility of the GenBank database.
To highlight its role in the global scientific community.
To outline the methods of data submission and retrieval.

Main Methods:

Data is submitted via web-based (BankIt) or standalone (Sequin) programs.
Daily data synchronization with the European Nucleotide Archive (ENA) and DNA Data Bank of Japan (DDBJ).
Access through the National Center for Biotechnology Information (NCBI) Entrez system, integrating various biological data types.

Main Results:

GenBank contains nucleotide sequences from over 380,000 organisms.
It provides integrated access to sequence data, taxonomy, genome information, and biomedical literature.
Tools like BLAST enable efficient sequence similarity searches.

Conclusions:

GenBank is an essential resource for molecular biology and genomics research.
Its continuous updates and global collaboration ensure comprehensive data coverage.
Integrated access and analysis tools enhance its utility for the scientific community.