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An Educational Video Demonstration of How to Prone a Critically Ill Intubated Patient
Published on: November 30, 2022
Do elderly patients fare well in the ICU?
Brian H Nathanson1, Thomas L Higgins2, Maura J Brennan2
1From OptiStatim, LLC, Longmeadow, MA.
Chest
|November 13, 2010
Summary
Advanced age alone is not a significant predictor of mortality in intensive care units (ICUs). Patient subgroup and comorbidities significantly influence survival rates, even in elderly patients.
Area of Science:
- Critical Care Medicine
- Geriatric Medicine
- Health Services Research
Background:
- A prior analysis of the Mortality Probability Model (MPM)-III indicated that 14% of intensive care unit (ICU) patients had age as their sole risk factor for hospital mortality.
- This specific subgroup exhibited a notably lower mortality rate (2%) compared to the overall ICU mortality rate (14%).
- Significant variations in mortality rates were observed among elderly patients based on their clinical profiles.
Purpose of the Study:
- To conduct an in-depth analysis of age-related mortality patterns in intensive care unit (ICU) patients.
- To investigate how patient stratification (surgical vs. medical) and the presence of additional risk factors modify the impact of age on mortality.
- To provide a nuanced understanding of mortality risk beyond chronological age in critical care settings.
Main Methods:
- Utilized data from Project IMPACT, encompassing 124,885 patients across 135 ICUs between 2001 and 2004.
- Stratified patients into elective surgical, emergency/unscheduled surgical, and medical categories.
- Further categorized patients by age groups and the presence or absence of additional MPM risk factors to assess mortality differentials.
Main Results:
- Mortality rates consistently increased with advancing age across all patient categories.
- Elective surgical patients without other risk factors demonstrated the lowest mortality (0.4% in 18-29 year olds to 9.2% in ≥90 year olds).
- Medical patients with additional risk factors exhibited the highest mortality (12.1% in 18-29 year olds to 36.0% in ≥90 year olds).
- Mortality in elective surgical patients aged 70s, 80s, and 90s approximately doubled (2.4% to 9.2%), while rising less dramatically in the medical group (27.0% to 36.0%).
Conclusions:
- While mortality increases with age, the specific patient subgroup significantly impacts risk, even among the elderly, suggesting potential selection bias.
- Advanced age itself should not be a barrier to ICU and surgical interventions.
- The presence of comorbidities substantially diminishes the likelihood of survival to discharge across all age groups.
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