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Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
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Published on: January 7, 2019

Do indicated preventive interventions for depression represent good value for money?

Cathrine Mihalopoulos1, Theo Vos, Jane Pirkis

  • 1Deakin University, Melbourne, Victoria, Australia. cathy.mihalopoulos@deakin.edu.au

The Australian and New Zealand Journal of Psychiatry
|November 16, 2010
PubMed
Summary
This summary is machine-generated.

Preventing depression is cost-effective. Brief bibliotherapy and group psychological interventions show good value for money in Australian general practice, warranting further evaluation.

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Area of Science:

  • Public Health
  • Health Economics
  • Mental Health Interventions

Background:

  • Depression prevention is a growing concern for researchers and policymakers.
  • The cost-effectiveness of depression prevention interventions at a population level is largely unknown.
  • Sub-syndromal depression screening in general practice can identify individuals for indicated prevention.

Purpose of the Study:

  • To assess the cost-effectiveness of two indicated depression prevention interventions.
  • To compare a brief bibliotherapy intervention with a comprehensive group-based psychological intervention.
  • To evaluate these interventions within the Australian health sector context.

Main Methods:

  • Economic modeling using a cost-utility framework.
  • Calculation of incremental cost-effectiveness ratios (ICERs) per disability-adjusted life year (DALY).
  • Probabilistic and univariate sensitivity analyses to assess uncertainty and robustness.

Main Results:

  • The brief bibliotherapy intervention had an ICER of AU$8600 per DALY.
  • The group-based psychological intervention had an ICER of AU$20 000 per DALY.
  • Both interventions were below the $50,000 per DALY cost-effectiveness threshold, with robust results.

Conclusions:

  • Both psychological interventions, especially bibliotherapy, are cost-effective for depression prevention post-screening in general practice.
  • These interventions merit further evaluation for routine care implementation.
  • Acceptability among primary care practitioners and administrators is crucial for widespread adoption.