Related Experiment Video

Updated: Jun 6, 2026

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix
10:21

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix

Published on: June 14, 2016

An unusual case of left ventricular aneurysm in duchenne muscular dystrophy

Xiaozhou Du1, Matthew Zeglinski, Nasir Shaikh

  • 1Institute of Cardiovascular Sciences, St, Boniface General Hospital, University of Manitoba, Winnipeg, Manitoba, Canada.

Cardiovascular Ultrasound
|November 16, 2010
PubMed

Insights

Duchenne muscular dystrophy (DMD) patients often develop heart disease. This report details a rare case of a left ventricular aneurysm in a 23-year-old male with DMD, highlighting an unusual cardiac complication.

Area of Science:

  • Cardiology
  • Neuromuscular Disorders
  • Medical Imaging

Background:

  • Duchenne muscular dystrophy (DMD) is a genetic disorder causing progressive muscle degeneration.
  • Cardiac involvement, particularly dilated cardiomyopathy, affects over 90% of adult DMD patients.
  • Ventricular aneurysms are an infrequently documented complication in DMD.

Observation:

  • A 23-year-old male patient with a confirmed diagnosis of Duchenne muscular dystrophy was evaluated.
  • Cardiac imaging revealed an aneurysm at the basal inferoposterior wall of the left ventricle.
  • This finding represents a rare manifestation of cardiac structural changes in DMD.

Findings:

  • The case highlights a specific type of left ventricular aneurysm in a DMD patient.
  • This contrasts with the more common dilated cardiomyopathy seen in this population.
  • The basal inferoposterior location of the aneurysm is noted.

Implications:

  • Recognizing rare cardiac complications like ventricular aneurysms is crucial for comprehensive DMD patient care.
  • Further research may elucidate the mechanisms behind aneurysm formation in DMD.
  • This case underscores the importance of detailed cardiac assessment in Duchenne muscular dystrophy patients.

More Related Videos

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China08:42

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography07:11

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography

Published on: October 28, 2020

Related Concept Videos

Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
Satellite Stem Cells and Muscular Dystrophy01:21

Satellite Stem Cells and Muscular Dystrophy

Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...