Related Experiment Video
Updated: Jun 6, 2026
06:18
Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
Published on: March 13, 2018
Chikungunya epidemic-related mortality.
S P Manimunda1, D Mavalankar, T Bandyopadhyay
1Regional Medical Research Centre (ICMR), Port Blair, Andaman and Nicobar Islands, India. sathyamanimunda@rediffmail.com
Epidemiology and Infection
|November 16, 2010
Summary
Chikungunya (CHIK) fever outbreaks can increase mortality, even when not directly registered. This study in Port Blair found a significant rise in expected deaths during the 2006 CHIK fever epidemic.
Area of Science:
- Epidemiology
- Public Health
- Infectious Diseases
Background:
- Port Blair experienced a chikungunya (CHIK) fever outbreak in 2006, affecting thousands.
- While no direct chikungunya deaths were recorded, global data suggests CHIK fever can be fatal.
Purpose of the Study:
- To investigate mortality trends in Port Blair from 2002-2008.
- To determine if the 2006 chikungunya epidemic was associated with increased mortality.
Main Methods:
- Calculated expected monthly deaths for 2006.
- Used average monthly mortality rates from 2002-2008 (excluding 2006) and the 2006 monthly population for calculations.
Main Results:
- A significant increase in expected deaths was observed during specific months in 2006.
- This rise in mortality coincided with the peak of the chikungunya fever epidemic.
Conclusions:
- The 2006 chikungunya outbreak in Port Blair was associated with a significant increase in overall mortality.
- This highlights the potential public health impact of chikungunya fever beyond directly registered fatalities.
Related Concept Videos
01:18Yellow Fever
Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...
01:29Malaria
Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
01:25Arboviral Encephalitis
Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
01:28Infectious Diseases and Their Occurrence
Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...