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Related Concept Videos

Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Translation01:31

Translation

Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Proteins are called the...
Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...

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Related Experiment Video

Updated: Jun 6, 2026

In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression
08:54

In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression

Published on: March 29, 2019

Translation by remote control.

Pascal Preker1, Torben Heick Jensen

  • 1Centre for mRNP Biogenesis and Metabolism, Department of Molecular Biology, C.F. Møllers Allé 3, Building 1130, Aarhus University, 8000 Aarhus, Denmark. pap@mb.au.dk

Cell
|November 16, 2010
PubMed
Summary

RNA polymerase II subunits Rbp4p and Rpb7p imprint messenger RNAs (mRNAs) during transcription. This imprinting process guides the mRNA transcripts to the translation machinery for protein synthesis.

Area of Science:

  • Molecular Biology
  • Gene Expression Regulation

Background:

  • Efficient gene expression necessitates the coordinated regulation of mRNA and protein synthesis.
  • The precise mechanisms guiding mRNA transcripts to the translation apparatus remain under investigation.

Discussion:

  • Harel-Sharvit et al. (2010) demonstrate that specific subunits of RNA polymerase II, namely Rbp4p and Rpb7p, play a crucial role in transcript processing.
  • These subunits are shown to transcriptionally imprint messenger RNAs (mRNAs) during their synthesis.

Key Insights:

  • Transcriptional imprinting by Rbp4p and Rpb7p serves as a key regulatory step in gene expression.
  • This imprinting mechanism facilitates the efficient recruitment of mRNA to the translation machinery, ensuring accurate protein synthesis.

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Insect-machine Hybrid System: Remote Radio Control of a Freely Flying Beetle (Mercynorrhina torquata)

Published on: September 2, 2016

Related Experiment Videos

Last Updated: Jun 6, 2026

In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression
08:54

In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression

Published on: March 29, 2019

Insect-machine Hybrid System: Remote Radio Control of a Freely Flying Beetle (Mercynorrhina torquata)
10:17

Insect-machine Hybrid System: Remote Radio Control of a Freely Flying Beetle (Mercynorrhina torquata)

Published on: September 2, 2016

Outlook:

  • Further research can elucidate the precise molecular interactions involved in Rbp4p/Rpb7p-mediated mRNA imprinting.
  • Understanding this process may reveal novel targets for modulating gene expression and protein production.