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Updated: Jun 6, 2026

Monochrome Multiplex Quantitative PCR Telomere Length Measurement

Monochrome Multiplex Quantitative PCR Telomere Length Measurement

Published on: March 22, 2024

Telomere length and cardiovascular disease.

Sébastien Saliques¹, Marianne Zeller, Julie Lorin

¹IFR Santé-STIC, UFR de Médecine et Pharmacie, Laboratoire de Physiopathologie et Pharmacologie Cardiovasculaires Expérimentales (LPPCE), Université de Bourgogne, 7, Boulevard Jeanne-d'Arc, 21000 Dijon, France. sebastien.saliques@gmail.com

Archives of Cardiovascular Diseases

|November 16, 2010

Summary

Telomere length, a marker of cellular aging, is increasingly linked to cardiovascular diseases like atherosclerosis and hypertension. Understanding this connection could reveal new cardiovascular risk markers.

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Telomere Length and Telomerase Activity; A Yin and Yang of Cell Senescence

Telomere Length and Telomerase Activity; A Yin and Yang of Cell Senescence

Published on: May 22, 2013

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Last Updated: Jun 6, 2026

Monochrome Multiplex Quantitative PCR Telomere Length Measurement

Monochrome Multiplex Quantitative PCR Telomere Length Measurement

Published on: March 22, 2024

Telomere Length and Telomerase Activity; A Yin and Yang of Cell Senescence

Telomere Length and Telomerase Activity; A Yin and Yang of Cell Senescence

Published on: May 22, 2013

Area of Science:

Cardiovascular Science
Genetics
Cell Biology

Background:

Telomeres, protective DNA structures at chromosome ends, shorten with cell division.
Telomere length is a marker of cellular senescence and organismal aging.
Growing evidence suggests telomere attrition is involved in cardiovascular disease (CVD) pathogenesis.

Purpose of the Study:

To review recent data on telomere length and cardiovascular disease.
To assess telomere length as a potential novel cardiovascular risk marker.

Main Methods:

Literature review of studies investigating telomere length in cardiovascular disease.
Analysis of factors influencing telomere length, including cardiovascular risk factors.

Main Results:

Telomere shortening is observed in conditions such as atherosclerosis, hypertension, and myocardial infarction.
Telomere length may serve as a prognostic indicator for cardiovascular events.
Cardiovascular risk factors like smoking, obesity, and oxidative stress influence telomere length.

Conclusions:

Telomere length is significantly associated with cardiovascular disease onset, progression, and prognosis.
Telomere length warrants further investigation as a valuable biomarker for cardiovascular risk assessment.