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Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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Published on: January 19, 2016

Replacing the 2'-oxygen with an exocyclic methylene group reverses the stabilization effects of α-L-LNA

Punit P Seth1, Charles R Allerson, Andres Berdeja

  • 1Department of Medicinal Chemistry, Isis Pharmaceuticals, Inc, 1891 Rutherford Road, Carlsbad, CA 92008, United States. pseth@isisph.com

Bioorganic & Medicinal Chemistry Letters
|November 16, 2010
PubMed

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