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Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator

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Dose error analysis for a scanned proton beam delivery system.

G Coutrakon¹, N Wang, D W Miller

¹Department of Physics, Northern Illinois University, DeKalb, IL 60115, USA. gcoutrakon@niu.edu

Physics in Medicine and Biology

|November 16, 2010

Summary

Proton therapy spot scanning systems show minimal dose errors, with root-mean-square (RMS) errors below 3% in each voxel. These findings confirm the technique

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Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Area of Science:

Medical Physics
Radiation Oncology
Particle Therapy

Background:

Particle beam scanning systems are susceptible to dose delivery errors from various sources.
Accurate dose delivery is critical for effective radiation therapy and minimizing side effects.

Purpose of the Study:

To quantify dose delivery errors in proton therapy spot scanning systems.
To assess the statistical dose errors within a defined target volume.

Main Methods:

Simulated dose delivery to an 8 × 10 × 8 cm³ water-equivalent target using Gaussian-shaped pencil beams.
Calculated root-mean-square (RMS) dose variations in 2.5 mm cubic voxels due to random proton energy, spot position, and intensity fluctuations.
Incorporated beam energy errors and scanning system hardware limitations into the analysis.

Main Results:

The spot scanning technique resulted in an RMS dose error of less than 2% or 3% in each voxel for a 2 Gy prescribed dose.
Statistical dose errors were calculated by simulating multiple treatment deliveries to the same target volume.
Errors were analyzed for random beam delivery uncertainties, including proton energy, spot position, and intensity.

Conclusions:

The analyzed spot scanning technique demonstrates high precision in dose delivery for proton therapy.
Calculated dose errors are within acceptable clinical limits for radiation therapy.
This study validates the safety and efficacy of spot scanning in proton beam radiation therapy.