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Related Concept Videos

Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
The Oral Microbiota01:27

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
Trichomoniasis01:18

Trichomoniasis

Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.
Peptic Ulcer Disease III: Clinical Manifestations and Complications01:25

Peptic Ulcer Disease III: Clinical Manifestations and Complications

Duodenal UlcersDuodenal ulcers are the most common form of peptic ulcer disease, presenting with chronic, intermittent epigastric pain. Pain typically appears 2–3 hours after meals, especially when the stomach is empty, often waking patients at night. It is characteristically relieved by food or antacids (“pain–food–relief”). Some patients remain asymptomatic until complications like bleeding or perforation emerge, particularly with NSAID or anticoagulant use.Gastric UlcersGastric ulcers share...

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Related Experiment Video

Updated: Jun 6, 2026

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
05:26

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

Published on: March 1, 2024

[Oral candidiasis: clinical features and control].

Tetsuya Yamamoto1

  • 1Department of Oral and Maxillofacial Surgery, Kochi Medical School, Kochi University, Nankoku 783-8505, Japan. yamamott@kochi-u.ac.jp

Rinsho Byori. the Japanese Journal of Clinical Pathology
|November 17, 2010
PubMed
Summary

Oral candidiasis, a common fungal infection, requires prompt management to prevent systemic spread. Treatment strategies may need adjustment for drug-resistant strains or compromised immunity.

Area of Science:

  • Mycology
  • Oral Medicine
  • Infectious Diseases

Context:

  • Candidiasis is a prevalent fungal infection, with oral candidiasis frequently presenting as an opportunistic condition.
  • Oral candidiasis manifests in acute, chronic, and lesion-associated forms, influenced by host factors.
  • Candida species, primarily Candida albicans, cause oral candidiasis, leading to inflammation and potential systemic dissemination.

Purpose:

  • To review the clinical presentation, causative agents, and management of oral candidiasis.
  • To highlight factors contributing to Candida adhesion and multiplication in the oral cavity.
  • To discuss treatment challenges, including drug resistance and immune suppression, and recommend advanced therapeutic approaches.

Summary:

  • Oral candidiasis is classified into acute, chronic, and lesion forms, often caused by Candida albicans.

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Curcuminoid-Mediated Antimicrobial Photodynamic Therapy on a Murine Model of Oral Candidiasis

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Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
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Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
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Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice

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Curcuminoid-Mediated Antimicrobial Photodynamic Therapy on a Murine Model of Oral Candidiasis
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  • Local factors like hyposalivation and poor oral hygiene, alongside systemic issues, promote Candida overgrowth.
  • Symptoms include inflammation, pain, and mucosal changes; rapid control is crucial to prevent systemic candidiasis.
  • Impact:

    • Effective management of oral candidiasis prevents dissemination to distant organs.
    • Understanding risk factors aids in preventing and treating this common opportunistic infection.
    • Addressing multi-drug resistant strains and host immune status is vital for successful therapeutic outcomes.