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Updated: Jun 6, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
A novel highly effective therapy for severe vasomotor symptoms in an estrogen deficient woman--case report
1The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA. laurie@ccivf.com
Purpose:
To describe a novel highly effective therapy for vasomotor symptoms associated with diminished oocyte reserve.
Methods:
A 58-year-old estrogen deficient woman with severe vasomotor symptoms was treated with 20 mg per day of dextroamphetamine sulfate.
Results:
A marked immediate improvement was noted.
Conclusions:
An acquired disorder of the sympathetic nervous system may be the etiologic factor for vasomotor symptoms in women with diminished egg reserve and treatment with sympathomimetic amines seems highly effective. This case will hopefully stimulate a larger series to determine its efficacy in a larger population.
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