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Published on: February 2, 2022
Palliative surgery for pancreatic carcinoma.
Iftikhar Mohammad Khan1, Mahmud Aurangzeb, Mujeeb-Ur-Rahman
1Surgical D Ward, Khyber Teaching Hospital, Peshawar. ifjee@hotmail.com
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|November 17, 2010
Summary
Palliative surgery for advanced pancreatic cancer offers improved quality of life. This study found surgical palliation associated with minimal complications and mortality in patients with unresectable pancreatic carcinoma.
Area of Science:
- Oncology
- Surgical Gastroenterology
Background:
- Advanced pancreatic carcinoma presents significant treatment challenges.
- Palliative surgical interventions are considered for symptom management and quality of life improvement.
Purpose of the Study:
- To evaluate the role and outcomes of palliative surgical treatment in patients diagnosed with advanced, unresectable pancreatic carcinoma.
Main Methods:
- A case series of 40 patients with advanced pancreatic carcinoma.
- Palliative procedures included triple bypass and various gastro-jejunostomy combinations.
- Exclusion criteria: resectable tumors and prior gastric/biliary surgery.
Main Results:
- Triple bypass was the most frequent procedure (52.5%).
- Complications included wound infection (7), biliary leakage (3), cholangitis (3), and delayed gastric emptying (5).
- Mortality occurred in 3 patients due to septicemia; median survival was 7.72 months.
Conclusions:
- Surgical palliation for advanced pancreatic cancer can enhance patient quality of life.
- The procedures demonstrated minimum morbidity and mortality in this patient cohort.
