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Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Intracranial cavernous angiomas
Syed Faraz Kazim1, Bhatti, Syed Ather Enam
1Section of Neurosurgery, Department of Surgery, The Aga Khan University Hospital, Karachi.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|November 17, 2010
Summary
Intracranial cavernous angiomas (CAs) present with seizures and focal deficits, often diagnosed via MRI. Pakistani patients may have a higher frequency of multiple CAs, with surgery indicated for severe symptoms.
Area of Science:
- Neurosurgery
- Neurology
- Vascular Malformations
Background:
- Intracranial cavernous angiomas (CAs) are vascular malformations.
- Understanding their presentation and management is crucial for patient outcomes.
Purpose of the Study:
- To describe the clinical presentation, diagnosis, and management of intracranial cavernous angiomas (CAs) in Pakistani patients.
- To evaluate the effectiveness of different diagnostic and treatment modalities.
Main Methods:
- Retrospective case series of 18 patients diagnosed with intracranial CAs.
- Data collected included demographics, clinical presentation, family history, diagnostic methods, management, and outcomes.
- Magnetic Resonance Imaging (MRI) was the primary diagnostic tool.
Main Results:
- The median age at diagnosis was 28.5 years, with females diagnosed younger than males.
- Seizures and focal neurologic deficits were the most common clinical manifestations.
- MRI demonstrated a high detection rate (93.8%) for CAs.
Conclusions:
- Cavernous angiomas (CAs) in Pakistani patients may present with a higher frequency of multiple lesions.
- Seizures and focal deficits are key clinical indicators.
- MRI is the most sensitive imaging modality for diagnosing intracranial CAs.
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