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Quantitative [18F]-Naf-PET-MRI Analysis for the Evaluation of Dynamic Bone Turnover in a Patient with Facetogenic Low Back Pain
Published on: August 8, 2019
Molecular mechanisms of bone 18F-NaF deposition
Johannes Czernin1, Nagichettiar Satyamurthy, Christiaan Schiepers
1Ahmanson Biological Imaging Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095-1782, USA. jczernin@mednet.ucla.edu
Abstract:
There is renewed interest in (18)F-NaF bone imaging with PET or PET/CT. The current brief discussion focuses on the molecular mechanisms of (18)F-NaF deposition in bone and presents model-based approaches to quantifying bone perfusion and metabolism in the context of preclinical and clinical applications of bone imaging with PET.
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