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Updated: Jun 6, 2026

Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis
Published on: March 25, 2016
Cutaneous CD4+/CD56+ hematodermic neoplasm
Ilkin Zindanci1, Mukaddes Kavala, Nesimi Buyukbabani
1Department of Dermatology, Goztepe Training and Resach Hospital, Istanbul, Turkey. ilkin.dr@gmail.com
Abstract:
CD4+/CD56+ hematodermic neoplasm, formerly known as blastic NK cell lymphoma, is a rare and aggressive neoplasm with a high incidence of cutaneous involvement, risk of leukemic dissemination and poor prognosis. The characteristic features are expression of the T helper inducer cell marker CD4 and the NK-cell marker CD56 in the absence of other T cell or NKcell specific markers. Because of the rarity of this disease, we describe a 48 year old woman suffering from CD4+/CD56+ hematodermic neoplasm on her cheek without leukemic infiltration.
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