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Regulatory ripples

Yasmine Belkaid1, Wanjun Chen

  • 1Mucosal Immunology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA. ybelkaid@niaid.nih.gov

Nature Immunology
|November 17, 2010
PubMed

Regulatory T cells come in many different forms depending on their mode of action or developmental origin. Data now show that interleukin 35, an immunomodulatory cytokine secreted by regulatory T cells, and interleukin 10 induce so-called 'iTR35 cells', which may have an important role in the phenomenon of infectious tolerance.

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