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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
General Anesthesia: Overview01:24

General Anesthesia: Overview

Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...

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Related Experiment Video

Updated: Jun 6, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Case report: bilateral angle closure glaucoma after general anesthesia.

Etienne Gayat1, Eric Gabison, Jean-Michel Devys

  • 1Department of Anesthesia and Intensive Care, Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.

Anesthesia and Analgesia
|November 18, 2010
PubMed
Summary

Acute angle closure glaucoma, a rare anesthesia complication, can cause blindness if not diagnosed promptly. This case highlights potential triggers like ephedrine during cervical spine surgery.

Related Experiment Videos

Last Updated: Jun 6, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Area of Science:

  • Ophthalmology
  • Anesthesiology
  • Neurosurgery

Background:

  • Acute angle closure glaucoma (AACG) is an uncommon but serious complication of general anesthesia.
  • Prompt diagnosis and intervention are crucial to prevent vision loss.

Observation:

  • A hypermetropic patient developed bilateral AACG after cervical spine surgery under general anesthesia.
  • The patient's hypermetropic eyes may have predisposed them to this complication.

Findings:

  • Ephedrine administration was identified as the most probable trigger for AACG in this case.
  • Nefopam and the prone surgical position were considered as potential contributing factors.

Implications:

  • This case underscores the importance of vigilance for AACG in patients undergoing surgery with general anesthesia, especially those with risk factors.
  • Anesthesiologists and surgeons should be aware of potential pharmacologic and positional triggers for AACG.