Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Calculation of Electric Flux01:25

Calculation of Electric Flux

Consider the electric field of an oppositely charged, parallel-plate system and an imaginary box between those plates. Let the bottom face of the box be ABCD, and the top face be FGHK. The electric field between the plates is uniform and points from the positive plate toward the negative plate. The calculation of this field's flux through the box's various faces shows that the net flux through the box is zero. Why does the flux cancel out here?
Interference and Diffraction02:18

Interference and Diffraction

Interference is a characteristic phenomenon exhibited by waves. When two electromagnetic waves interact with their peaks and troughs coinciding, a resulting wave with enhanced amplitude is produced. This is known as constructive interference. In this case, the two waves interacting are in phase with each other.
Dose Size and Dosing Frequency: Determination Methods01:21

Dose Size and Dosing Frequency: Determination Methods

Determining the optimal dose size and dosing frequency in pharmacotherapy is crucial for achieving therapeutic effectiveness while minimizing adverse effects. This article explores the methodologies employed in determining these parameters, focusing on their significance and interplay to tailor dosing regimens.Dose Size: Dose size refers to the amount of a drug administered in a single dose. It is determined based on the drug's pharmacodynamics and pharmacokinetics properties and...
Convolution Properties I01:20

Convolution Properties I

Convolution computations can be simplified by utilizing their inherent properties.
The commutative property reveals that the input and the impulse response of an LTI (Linear Time-Invariant) system can be interchanged without affecting the output:
Convolution Properties II01:17

Convolution Properties II

The important convolution properties include width, area, differentiation, and integration properties.
The width property indicates that if the durations of input signals are T1 and T2, then the width of the output response equals the sum of both durations, irrespective of the shapes of the two functions. For instance, convolving two rectangular pulses with durations of 2 seconds and 1 second results in a function with a width of 3 seconds.
The area property asserts that the area under the...
Atomic Absorption Spectroscopy: Radiation and Light Sources01:13

Atomic Absorption Spectroscopy: Radiation and Light Sources

Atomic absorption spectroscopy (AAS) relies on the Beer-Lambert law, which requires that the radiation source emits a narrow range of wavelengths to match the absorption characteristics of the analyte atom. The primary criteria for choosing an appropriate radiation source in AAS is to provide a precise and intense emission at specific wavelengths that will allow accurate detection of the analyte.
Two common narrow-range 'line' sources used in AAS are hollow-cathode lamps (HCLs) and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dual regulatory roles and mechanisms of Gamma delta T cells in organ fibrosis.

Tissue & cell·2026
Same author

Revisiting the genome assembly of Lupinus species reveals differential diploidization after a shared whole-genome duplication.

G3 (Bethesda, Md.)·2026
Same author

Latent Accelerated Diffusion-based Deformation Estimation for Real-time Volumetric Imaging.

Physics in medicine and biology·2026
Same author

A WEb-Accessible comprehensiVE platform for automatic vestibular schwannoma segmentation and longitudinal volumetric tracking.

Neuro-oncology advances·2026
Same author

The impact of intelligent manufacturing strategy on enterprise labor productivity: evidence from a quasi-natural experiment in China.

Frontiers in artificial intelligence·2026
Same author

Qilin Pills protect against diminished ovarian reserve by suppressing pathological overactivation of PINK1/Parkin-mediated mitophagy in granulosa cells.

Journal of ethnopharmacology·2026
Same journal

Deep learning-based dose prediction to enhance planning efficiency in cervical brachytherapy with hybrid applicators.

Physics in medicine and biology·2026
Same journal

Corrigendum: Referenceless MR thermometry-a comparison of five methods (2017<i>Phys. Med. Biol</i>.<b>62</b>1-16).

Physics in medicine and biology·2026
Same journal

Corrigendum: Measured and Monte Carlo simulated electron backscatter to the monitor chamber for the varian TrueBeam linac (2016<i>Phys. Med. Biol</i>.<b>61</b>8779).

Physics in medicine and biology·2026
Same journal

Corrigendum: 3D range-modulator for scanned particle therapy: development, Monte Carlo simulations and experimental evaluation (2017<i>Phys. Med. Biol</i>.<b>62</b>7075).

Physics in medicine and biology·2026
Same journal

Recent progress in applications of computing to radiotherapy (ICCR 2016).

Physics in medicine and biology·2026
Same journal

Novel TMS coils designed using an inverse boundary element method.

Physics in medicine and biology·2026
See all related articles

Related Experiment Video

Updated: Jun 6, 2026

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator
07:31

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator

Published on: May 9, 2014

Fluence-convolution broad-beam (FCBB) dose calculation.

Weiguo Lu1, Mingli Chen

  • 1TomoTherapy Inc., Madison, WI 53717, USA. wlu@tomotherapy.com

Physics in Medicine and Biology
|November 18, 2010
PubMed
Summary
This summary is machine-generated.

A new dose calculation algorithm for Intensity-Modulated Radiation Therapy (IMRT) optimization is faster and uses less memory. It achieves accuracy within 5% of standard methods, making it suitable for IMRT dose calculations.

Related Experiment Videos

Last Updated: Jun 6, 2026

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator
07:31

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator

Published on: May 9, 2014

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Computational Biology

Background:

  • Intensity-Modulated Radiation Therapy (IMRT) optimization demands efficient dose calculation algorithms.
  • Existing methods often face trade-offs between speed, accuracy, and memory usage.

Purpose of the Study:

  • To develop a novel, fast, and memory-efficient dose calculation algorithm for IMRT optimization.
  • To validate the algorithm's accuracy against established methods.

Main Methods:

  • Decomposition of the infinitesimal pencil beam (IPB) kernel into central axis (CAX) and lateral spread function (LSF).
  • Development of a non-voxel, non-beamlet-based dose calculation formula using beam's eye view (BEV).
  • Commissioning of LSF and CAX using the collapsed-cone convolution/superposition (CCCS) method as the standard.

Main Results:

  • The proposed algorithm achieves O(N(3)) complexity, significantly outperforming CCCS in speed.
  • Memory implementation is orders of magnitude smaller than conventional voxel-based beamlet-superposition (VBS) methods.
  • Agreement within 3% for homogeneous phantoms and 5% for heterogeneous/clinical cases compared to CCCS.

Conclusions:

  • The developed algorithm offers a substantial improvement in speed and memory efficiency for IMRT dose calculations.
  • Its accuracy is clinically acceptable, making it suitable for iterative dose calculations during IMRT optimization.
  • The algorithm provides a viable alternative for demanding IMRT planning workflows.