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Updated: Jun 6, 2026

Comet Assay to Quantify DNA Damage in FLT3 Mutant-expressing 32D Cells after Exposure to Type I and Type II FLT3 Inhibitors
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Published on: October 17, 2025

Clofarabine in leukemia.

Hady Ghanem1, Elias Jabbour, Stefan Faderl

  • 1Department of Leukemia, The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA. hadyghanem@hotmail.com

Expert Review of Hematology
|November 19, 2010
PubMed
Summary

Clofarabine, a purine nucleoside analogue, inhibits DNA replication and shows antitumor activity in acute leukemia. Its enhanced stability and phosphorylation affinity make it a promising agent for hematologic and solid tumors.

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