Strategies for electrochemical detection in immunochemistry

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ELIME (Enzyme Linked Immuno Magnetic Electrochemical) Method for Mycotoxin Detection
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Sonia Centi1, Serena Laschi, Marco Mascini

  • 1Università degli Studi di Firenze, Dipartimento di Chimica, Polo Scientifico, via della Lastruccia 3, 50019 Sesto Fiorentino, Firenze, Italy.

Bioanalysis
|November 19, 2010
PubMed

In this review, the current status of research in electrochemical immunosensors is considered. We primarily focus on label-free and enzyme-labeled immunosensors, and the analytical capabilities of these devices are discussed. Moreover, the use of magnetic beads as new materials for immunosensors coupled with electrochemical sensing is also described, together with the application of new molecules such as aptamers as specific biorecognition elements. Examples of the applicability of these devices in solving various analytical problems in clinical, environmental and food fields are reported. Finally, the prospects for the further development of immunosensor technologies are shown.

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