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Related Concept Videos

Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Drug Dosage Regimen: Overview01:15

Drug Dosage Regimen: Overview

A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
Drug Delivery: Overview01:16

Drug Delivery: Overview

The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the gastrointestinal...

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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Excessive medical information increase in package inserts.

J Fuchs1, S Werner, C Scheunpflug

  • 1PAINT-Consult®, Jena, Germany. joerg.fuchs@paint-consult.com

International Journal of Clinical Pharmacology and Therapeutics
|November 19, 2010
PubMed
Summary
This summary is machine-generated.

Patient medicine information in package inserts has increased in length and complexity, failing to meet patient needs. Pharmaceutical companies and regulators must simplify texts for better patient comprehension and essential information delivery.

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Area of Science:

  • Pharmaceutical Information
  • Patient Education
  • Health Literacy

Background:

  • Package inserts are a primary source of medicine information for patients.
  • The complexity and volume of information in these inserts have grown over time.

Purpose of the Study:

  • To evaluate the quality and readability of German package inserts.
  • To assess if current package inserts meet patient information requirements.

Main Methods:

  • Analysis of 271 German package inserts from 2005.
  • Application of 152 quality criteria and measurement of 242 values.

Main Results:

  • Average text length increased to 2,005 words, with an average of 114.1 difficult words and 46.3 non-quantifiable phrases.
  • Inconsistent presentation of dosage information (60.1%), maximum daily dose (29.5%), side effect actions (54.6%), and numerical frequency of side effects (24.2%).

Conclusions:

  • Current package inserts provide excessive and complex information, hindering patient understanding.
  • Pharmaceutical companies, authorities, and legislators must collaborate to essentialize and simplify patient medicine information.