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Updated: Jun 6, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Experience with outpatient computed tomographic-guided renal biopsy
A Margaryan1, M A Perazella, R L Mahnensmith
1Section of Nephrology, Yale School of Medicine, New Haven, CT, USA.
Outpatient CT-guided kidney biopsy is a safe and effective procedure, yielding adequate diagnostic tissue with minimal complications. This approach allows for shorter observation periods, improving patient care.
Area of Science:
- Nephrology
- Radiology
- Medical Procedures
Background:
- Native kidney biopsies are traditionally performed with inpatient hospital stays.
- Outpatient procedures may offer advantages in efficiency and patient comfort.
Purpose of the Study:
- To evaluate the efficacy and safety of outpatient Computed Tomographic (CT)-guided native kidney biopsies.
- To assess complication rates and diagnostic yield in an outpatient setting.
Main Methods:
- Retrospective review of 146 outpatient CT-guided renal biopsies performed between 1995 and 2001.
- Analysis of patient demographics, clinical data, procedure details, and complications.
- Assessment of diagnostic tissue adequacy and post-procedure observation times.
Main Results:
- Diagnostic tissue was obtained in 98.6% of cases.
- The procedure was well-tolerated with no significant hemodynamic changes.
- Only 1 patient required transfusion; 6 experienced detectable bleeding requiring hospitalization for observation. No deaths or interventions were reported.
Conclusions:
- Outpatient CT-guided native kidney biopsy is a safe and effective procedure.
- It provides adequate diagnostic tissue with a very low complication rate.
- A 4-6 hour observation period appears sufficient for most patients.
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