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Updated: Jun 6, 2026

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
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Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

Semi-automatic segmentation for prostate interventions.

S Sara Mahdavi1, Nick Chng, Ingrid Spadinger

  • 1Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC, Canada. saram@ece.ubc.ca

Medical Image Analysis
|November 19, 2010
PubMed
Summary
This summary is machine-generated.

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This study introduces a semi-automatic method for prostate segmentation in brachytherapy, significantly reducing contouring time and subjectivity. The approach uses a warped ellipsoid model, achieving accurate prostate delineation for improved treatment planning.

Area of Science:

  • Medical Imaging
  • Radiation Oncology
  • Computational Anatomy

Background:

  • Accurate prostate segmentation is crucial for effective brachytherapy.
  • Manual segmentation is time-consuming and prone to inter-observer variability.
  • Existing methods may lack the speed and consistency required for routine clinical use.

Purpose of the Study:

  • To develop and characterize a semi-automatic prostate segmentation method for brachytherapy.
  • To improve the efficiency and consistency of prostate gland delineation in ultrasound images.
  • To reduce subjectivity in segmentation compared to manual methods.

Main Methods:

  • A semi-automatic method using a warped and tapered ellipsoid as an a-priori 3D prostate shape.
  • Transforming endorectal transverse images into ellipses to solve the shape fitting problem as a convex optimization problem.

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  • Validation through comparison with manual contours and assessment of segmentation time and observer variability.
  • Main Results:

    • Achieved an average whole gland error of 6.63 ± 0.9% compared to manual contours.
    • Reported a whole gland volume error of 5.82 ± 4.15% after physician modification.
    • Reduced segmentation inter- and intra-observer variability from 4.65% and 5.95% to 3.04% and 3.48%, respectively.
    • Total segmentation time, including initialization and potential modification, is under 4 minutes, significantly faster than manual methods.

    Conclusions:

    • The semi-automatic segmentation method is fast, consistent, and accurate for prostate delineation in ultrasound images.
    • The method reduces subjectivity and observer variability in segmentation.
    • It is successfully integrated into the standard treatment routine for low dose rate prostate brachytherapy at the British Columbia Cancer Agency.