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Granulomatous amebic encephalitis in a child with acute lymphoblastic leukemia successfully treated with multimodal
P Maritschnegg1, P Sovinz, H Lackner
1Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Auenbruggerplatz 30, 8036 Graz, Austria. peter.maritschnegg@meduni-graz.at
Journal of Clinical Microbiology
|November 19, 2010
Abstract:
Acanthamoeba is the causative agent of granulomatous amebic encephalitis, a rare and usually fatal disease. We report a child with acute lymphoblastic leukemia who developed brain abscesses caused by Acanthamoeba during induction therapy. Multimodal antimicrobial chemotherapy and hyperbaric oxygen therapy resulted in complete resolution of symptoms and of pathology as seen by magnetic resonance imaging.
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