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Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution
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[DNA methylation and cancer metastasis]

Kazuyuki Kawakami1, Toshinari Minamoto

  • 1Division of Translational and Clinical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.

Gan to Kagaku Ryoho. Cancer & Chemotherapy
|November 19, 2010
PubMed
Summary

Cancer cells gain metastatic abilities through DNA methylation changes. Aberrant DNA methylation, including promoter hypermethylation and global hypomethylation, drives cancer spread and offers targets for molecular diagnosis.

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