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Related Concept Videos

Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.
Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
Evolution of New Traits in Microbes01:24

Evolution of New Traits in Microbes

Microorganisms evolve rapidly due to their large population sizes and short generation times, often exhibiting measurable changes within days under laboratory conditions. Natural selection acts on standing genetic variation, enabling the retention and amplification of beneficial traits that confer fitness advantages in changing environments.Adaptive Pigment Regulation in RhodobacterIn Rhodobacter, a genus of purple non-sulfur bacteria, light-harvesting pigments such as bacteriochlorophyll and...
Synthetic Biology02:55

Synthetic Biology

Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...

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Related Experiment Video

Updated: Jun 6, 2026

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
09:40

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Published on: June 11, 2015

Phenomics: the next challenge.

David Houle1, Diddahally R Govindaraju, Stig Omholt

  • 1Department of Biological Science, Florida State University, Tallahassee, 32306-4295, USA. dhoule@bio.fsu.edu

Nature Reviews. Genetics
|November 19, 2010
PubMed
Summary
This summary is machine-generated.

Understanding biological traits requires comprehensive phenomic data, which is currently lacking. Developing phenomics as a distinct field is crucial for advancing high-throughput phenotyping and studying genotype-phenotype interactions.

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Last Updated: Jun 6, 2026

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Published on: May 9, 2017

Area of Science:

  • Biology
  • Genetics
  • Evolutionary Biology

Background:

  • Understanding phenotypic characteristics (health, disease, fitness) is a core biological goal.
  • Phenotypic variation arises from complex genotype-environment interactions.
  • A detailed 'genotype-phenotype' map requires extensive phenotypic data.

Purpose of the Study:

  • To highlight the critical need for detailed phenotypic data.
  • To advocate for phenomics as an independent scientific discipline.
  • To promote the development of high-throughput and high-dimensional phenotyping.

Main Methods:

  • This study is a conceptual review and does not involve experimental methods.
  • It analyzes the current state of phenotyping relative to genomics.
  • It discusses the requirements for studying genotype-phenotype relationships.

Main Results:

  • The characterization of individual phenomes lags significantly behind genome characterization.
  • Current phenotyping capabilities are insufficient for comprehensive genotype-phenotype mapping.
  • There is a recognized gap in the systematic study of phenomics.

Conclusions:

  • Phenomics should be established as a distinct scientific discipline.
  • Advancing phenomics is essential for understanding biological complexity.
  • The development of advanced phenotyping technologies is imperative.