Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Inflammatory epithelial changes and nonviral cervicovaginal pathogens.

L E Frisch1, L D Buckley, S A Chalem

  • 1Student Health Service, Southern Illinois University, Carbondale.

Acta Cytologica
|March 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical Conversations on Diseases of the Skin.

Buffalo medical and surgical journal·2023
Same author

Enhancing influenza immunization. Postcard and telephone reminders and the challenge of immunization site shift.

Archives of family medicine·2000
Same author

Naked-eye inspection of the cervix after acetic acid application may improve the predictive value of negative cytologic screening.

The Journal of family practice·1994
Same author

Cervicography: an intermediate triage test for the evaluation of cervical atypia.

The Journal of family practice·1993
Same author

Cervicography: adjunctive cervical cancer screening by primary care clinicians.

The Journal of family practice·1993
Same author

Improving the sensitivity of cervical cytologic screening. A comparison of duplicate smears and colposcopic examination of patients with cytologic inflammatory epithelial changes.

Acta cytologica·1990

Inflammatory epithelial changes (IECs) in cervical smears are linked to higher rates of Chlamydia infection and elevated vaginal pH. These findings suggest a need to re-evaluate current treatment guidelines for IEC.

Area of Science:

  • Gynecology
  • Infectious Diseases
  • Cytopathology

Background:

  • Cervicovaginal infections can present with inflammatory epithelial changes (IECs) on cytologic examination.
  • The association between IECs and specific infections like Chlamydia requires further investigation.
  • Current management of IECs often involves empirical treatment, which may not always be necessary.

Purpose of the Study:

  • To determine the prevalence of specific cervicovaginal infections and elevated vaginal pH in women with cytologic diagnoses of IEC.
  • To compare infection rates and pH levels between women with IECs and a control group.
  • To assess the utility of current treatment guidelines for IECs.

Main Methods:

  • A case-control study involving 249 women with cytologic diagnoses of IEC and 211 controls.

Related Experiment Videos

  • Microbiological testing for Chlamydia, Monilia, and Trichomonas.
  • Vaginal pH measurement.
  • Comparison of infection prevalence and pH between cases and controls.

    • Main Results:

    • Chlamydia infection was found in 15.7% of IEC cases, significantly higher than in controls (7.6%).
    • Elevated vaginal pH (>5.5) was observed in 29.7% of IEC cases, compared to 10.7% in controls.
    • Prevalence of Monilia and Trichomonas did not differ significantly between groups.

    Conclusions:

    • The study highlights a significant association between IECs and Chlamydia infection, as well as elevated vaginal pH.
    • Findings challenge the routine empirical treatment of IECs, suggesting a need for targeted diagnostic approaches.
    • Reevaluation of current clinical guidelines for managing IECs is warranted based on these results.